Advances in Experimental Medicine
and Biology

Advances in Experimental Medicine
and Biology

MICROBIOLOGY

In the last decades, several viruses emerged, after
cross-species passage from animal reservoirs and
then spreading in human populations; the Ebola
virus, two different coronaviruses causing the
severe acute respiratory syndrome (SARS-CoV)
and the Middle-east respiratory syndrome
(MERS-CoV), and the Nipah virus, are
paradigmatic examples of biological agents
completely new for humans, with high epidemic
potential, but also prone to disappear in case
early detection and intervention are ensured
(Morse 1993; Fauci and Morens 2012).
Other viruses expanded their geographical
area of activity from the original ecological
niche to new lands and continents, as recently
demonstrated by the large outbreaks of Zika or
Crimean-Congo haemorrhagic fever in Spain,
and dengue in Madeira (Portugal). Several
arboviruses represent paradigmatic examples of
microorganisms which found the conditions for
their spread in previously unaffected areas
inhabited by completely susceptible population

Irun R. Cohen, The Weizmann Institute of Science, Rehovot, Israel
N.S.AbelLajtha,KlineInstituteforPsychiatric Research,Orangeburg,NY,USA
John D. Lambris, University of Pennsylvania, Philadelphia, PA, USA
Rodolfo Paoletti, University of Milan, Milan, Italy

Springer International Publishing AG

2017

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